Update on Integrative-Based Research

“Happy feet”: evaluating the benefits of a 100-day 10,000 step challenge on mental health and wellbeing.

Link to study

This study investigated the impact of a 100-day, 10,000 step program on signs of depression, anxiety, and stress as well as general wellbeing. The researchers found that setting this goal resulted in improvements in all measures of mental health. Interestingly, this effect appeared irrespective of whether a person reached the 10,000 step mark. This study provides further support for advocating increased physical activity in our clients to improve their mental wellbeing.

Fasting Glucose and the Risk of Depressive Symptoms: Instrumental-Variable Regression in the Cardiovascular Risk in Young Finns Study.

Link to study

In this study, the researchers investigated the relationship between blood glucose levels and depressive symptoms in 1,200 adults. They found that low glucose levels (but not high glucose) may be linked to depressive symptoms. Further support for the importance of food, diet, and mental health!

A Meta-Analysis of Cytokine Concentrations in Eating Disorders.

Link to study

In this meta-analysis, the authors analysed 25 studies examining the relationship between inflammation and eating disorders (mostly anorexia nervosa). They concluded that the evidence strongly suggests higher levels of inflammatory biomarkers in people with anorexia.

Here is one of their statements from the review: “Considering the role of cytokines in appetite, mood regulation, and anxiety, these pro-inflammatory cytokines could be a potential future drug target to help people with AN, not only with weight gain but also with various coexisting psychological problems.”

…. Maybe they should also be considering ‘anti-inflammatory’ lifestyle, dietary, nutraceutical, and emotional coping strategies … not just drugs!

Prevalence of Prescription Medications With Depression as a Potential Adverse Effect Among Adults in the United States”

Link to study

In this cross-sectional study, prescription medications that have depression as a potential adverse effect were shown to be commonly used. Alarmingly, the estimated prevalence of depression was 15% for those reporting use of 3 or more medications with depression as an adverse effect vs 4.7% for those not using such medications.

We, therefore, must always consider the potential impact a prescription medication may have on our mood.