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Research is continuing to confirm the important bi-directional relationship between the gut and the brain. In fact, treating the gut is proving to be an effective way to reduce depression, anxiety, and other mood disorders in adults. In a recent review paper, it was concluded that probiotics may be an effective treatment for adults depression. (see blog)
It is estimated that post-natal (postpartum) depression affects up to 15% of mums. Unfortunately, pharmaceutical and herbal treatment options are limited given concerns about the potential impact on newborns. As a result, finding an effective safe option is important. It seems that probiotics could be that option.
In this randomised, double-blind, placebo-controlled study, 423 women were given a daily probiotic (Lactobacillus rhamnosus HN001) or a placebo during pregnancy (from 14 weeks gestation) until 6 months postpartum. Its effects on maternal depression and anxiety in the postpartum period was examined.
Mothers in the probiotic group reported significantly lower depression and anxiety scores compared to the placebo. What is exciting is that the effects were clinically meaningful as there were large treatment effect sizes of 1·2 for depression and 1·0 for anxiety.
This study adds to the body of evidence supporting the mood-lifting effects of probiotics in adults. The results indicate that probiotics may be helpful for the prevention or treatment of symptoms of depression and anxiety postpartum. In addition, benefits have the potential to transfer to the health of the newborn although further research is required.
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